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Selecting healthy embryos: PGD and PGS

Preimplantation genetic diagnosis (PGD) is a contemporary method to increase efficiency of transfers and to decrease the burden on patients.

According to research, up to 50% of transferred embryos carry chromosomal defects, due to which pregnancy is not achieved or is miscarried. With the help of PGS/PGD testing, embryos with chromosomal defects can be identified and only healthy embryos can be selected for transfer, providing a higher probability for successful IVF/ICSI treatment and less emotional stress for the patient.

Preimplantation Genetic Diagnosis (PGD) allows to minimize the risk of genetic diseases transmission on to the child by already before embryo transfer and becoming pregnant. The method may only be carried out during an IVF procedure, but it enables to identify abnormalities in egg cell DNA before embryo is transferred to the uterus.

PGD and PGS – contemporary methods in fertility treatment

Preimplantation Genetic Screening (PGS) is used in conjunction with in-vitro fertilization (IVF) to screen embryos for numerical chromosomal abnormalities prior to transfer. The information obtained using this method helps IVF physicians and patients decide which embryos to transfer. These methods are recommended for couples, who have failed IVF cycles, have miscarried or are in risk to pass on a genetic disease.

With PGD/PGS it is possible to diagnose cystic fibrosis, sickle cell anemia, Down syndrome, Huntington’s disease, Fragile-X, spinal muscular atrophy, hemophilia A, Duchenne muscular dystrophy and other genetic diseases.

PGS is a contemporary method to discover non-suitable embryos early on.
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